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SAR-020106

Glpbio
Catalog No:GC61266-10mM (in 1mL DMSO) CAS No.:1184843-57-9 MDLNo:C19H19ClN6O Brand:Glpbio purity: 特性: Purpose:SAR-020106是一种ATP竞争性的、选择性好的CHK1抑制剂,IC50为13.3nM。SAR-020106对CHK2具有良好的选择性。SAR-020106在几种结肠肿瘤细胞系中以p53依赖性方式将Gemcitabine和SN38的细胞杀伤力提高了3.0到29倍。SAR-020106可通过选择抗癌药物增强抗肿瘤活性。DMSO: 5 mg/mL (13.06 mM; Need ultrasonic)
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Product Overview
Product Name SAR-020106
CAS1184843-57-9
MW382.85
MDLC19H19ClN6O
Storage conditionPowder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
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